We also measured the brain, the hippocampus... What we found was that among the kids with Type 2 diabetes, their hippocampi are smaller in volume, very significantly. For those of you who work in Alzheimer's disease, the difference between the kids with Type 2 diabetes and the control kids [who were obese but did not have Type 2 diabetes] is about the same as that between a normal elderly and one with mild cognitive impairment. So the volume difference is around 12% So this is not a small, little thing. So what will happen to these children, whether we're actually seeing permanent damage or not, we don't know.I haven't watched the entire lecture, but I gather that the reason he tells us to remember that the control group is obese is that we can also expect to see brain changes in obese teens who have not developed Type 2 diabetes, which would mean that the brains of teenagers with Type 2 diabetes are even more different from the brains of normal-weight adolescents.*
Their frontal lobe regions are also affected, and they have more overall brain atrophy than the control group. And remember, the control group was an obese control group.
Impact of Obesity and Metabolic Disease on Brain Structure and Function 5/5/11
Antonio Convit, M.D.
The lecture - the few minutes I've watched of it - is horrifying.
I had no idea.
Right. Obesity in and of itself, without Type 2 diabetes, is linked to brain atrophy. Sounds like overweight may be as well, at least in people over 70.
They found that obese individuals [over age 70] had, on average, 8 percent less brain tissue than people of normal weight, while overweight people had 4 percent less tissue. According to Thompson, who is also a member of UCLA's Laboratory of Neuro Imaging, this is the first time anyone has established a link between being overweight and having what he describes as "severe brain degeneration."btw, remember back when I was bugging everyone about vegan diets making you thin?
"That's a big loss of tissue, and it depletes your cognitive reserves, putting you at much greater risk of Alzheimer's and other diseases that attack the brain," he said. "But you can greatly reduce your risk for Alzheimer's if you can eat healthily and keep your weight under control."
Well, they do. I adopted a vegan weight-loss diet in September 2009, lost 11 pounds, and have basically kept it off ever since -- without even being a vegan. I need to get back on track, but still: even part-time veganism makes you thinner than full-time non-veganism.